Recombinant CD16-2/FCGR4 Monoclonal Antibody (AN300462P)
For research use only.
| Verified Samples |
Verified Samples in IF: RAW2647 Verified Samples in FCM: Raw264.7 |
| Dilution | ICC/IF 1:50-1:1000, FCM 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse |
| Applications | FCM, ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse FCGR4 protein |
| Abbre | FCGR4 |
| Synonyms | Fcgr, Fcgr4, 4833442P21Rik, 4833442P21Rik Protein, CD16-2, CD16-2 Protein, FcgammaRIV, FcgammaRIV Protein, Fcgr3a, Fcgr3a Protein, FcgRIV, FcgRIV Protein, Fcrl3, Fcrl3 Protein, Low Affinity Immunoglobulin Gamma Fc Region Receptor IV, Mouse |
| Swissprot | |
| Tissue Specificity | Detected on myeloid cells, peripheral blood monocytes, splenic and bone marrow dendritic cells, and thioglycollate-elicited macrophages and neutrophils but absent from lymphoid populations with no expression observed on T cells, B cells, NK cells or other granulocytes (at protein level) |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Clone No. | 8B6 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | FcgRIV, also known as CD16-2, is an intermediate-affinity activating receptor for IgG2a and IgG2b. CD16-2 is the mouse homolog of human FcgRIIIA. CD16-2 is a low-affinity IgE receptor for all allotypes and the ligation of FcgRIV by antigen-IgE immune complexes promotes macrophage-mediated phagocytosis and is involved in lung inflammation. |
Other Clones
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Other Formats
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Unconjugated
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