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Recombinant Caspase-14/CASP14 Monoclonal Antibody (AN300033P)

All Size Price Qty
100μL $ 380.00
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For research use only.

Verified Samples Verified Samples in IHC: Human skin
Verified Samples in IF: Hela
Dilution IHC-P 1:100-1:500,  ICC/IF 1:20-1:100,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P,  ICC/IF
Clonality Rabbit Monoclonal
Immunogen Recombinant Human Caspase-14 / CASP14 protein
Abbre CASP14
Synonyms ARCI,  Caspase,  CASP14,  ARCI12,  CASP-14,  Caspase-14,  MGC119078,  MGC119079
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Cell Biology
Clone No. 8D5
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 7 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
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Unconjugated

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