Recombinant Carbonic Anhydrase IV/CA4 Monoclonal Antibody (AN300189P)

For research use only.
Verified Samples | Verified Samples in IHC: Human lung, Human kidney |
Dilution | IHC-P 1:100-1:500, |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC-P |
Clonality | Rabbit Monoclonal |
Immunogen | Recombinant Human Carbonic Anhydrase IV / CA4 protein |
Abbre | CA4 |
Synonyms | CAH, Car, CA IV, CAH4, CAIV, CA-IV, Car4, Carbonate dehydratase IV, Carbonic anhydrase 4, Carbonic Anhydrase IV, Carbonic dehydratase, Carbonic dehydratase IV, EC 4.2.1.1, Retinitis pigmentosa 17 (autosomal dominant), RP17, CA4 |
Swissprot | |
Concentration | 1 mg/mL |
Buffer | 0.2 μm filtered solution in PBS |
Purification Method | Protein A |
Research Areas | Neuroscience |
Clone No. | 5C10 |
Conjugation | Unconjugated |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Shipping | Ice bag |
background | The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase IV (CAIV) is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage. CAIV is a high-activity isozyme in CO2 hydration comparable to that of CAII. Furthermore, CAIV is more active in HCO3- dehydration than is CAII. However, the esterase activity of CAIV is decreased 150-fold compared to CAII. |
Other Clones
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Unconjugated
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