Recombinant c-Kit/CD117 Monoclonal Antibody (AN300410P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human skin, Human melanoma, Human breast cancer |
| Dilution | IHC-P 1:100-1:500 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human c-Kit/CD117 protein |
| Abbre | KIT |
| Synonyms | KIT, C-Kit, CD117, PBT, SCFR, Mast/stem cell growth factor receptor Kit, p145 c-kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, SCFR, C Kit, CD_antigen: CD117, c-Kit Ligand, Kit Ligand, KIT oncogene, KIT proto oncogene receptor tyrosine kinase, KIT proto-oncogene receptor tyrosine kinase, Mast cell growth factor receptor, MGF, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, SCF Receptor, soluble KIT variant 1, Steel Factor Receptor, Stem cell factor receptor, tyrosine protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein |
| Swissprot | |
| Cellular Localization | Cell membrane, Cytoplasm |
| Tissue Specificity | Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Immunology, Tags & Cell Markers, Signal Transduction, Neuroscience, Stem Cells, Cancer, Developmental Biology |
| Clone No. | 5D9 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Unconjugated
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