Recombinant Bovine TGFBR1 protein (His Tag) (PDEB100010)
For research use only.
| Synonyms | AAT5, ACVRLK 4, ALK 5, Activin A receptor type II like kinase 53kDa, Activin receptor like kinase 5, LDS1A, MSSE, SKR4, Serine/threonine-protein kinase receptor R4, TGF beta Receptor I, TGFR 1, TbetaR-I |
| Species | Bovine |
| Expression Host | E.coli |
| Sequence | Ile143-Leu330 |
| Accession | O46680 |
| Calculated Molecular Weight | 20.6 kDa |
| Observed Molecular Weight | 20 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. |
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