Recombinant BMP-4 Monoclonal Antibody (AN301282L)

For research use only.
Verified Samples | Verified Samples in IHC: Human appendix |
Dilution | IHC 1:200-1:1000 |
Isotype | IgG,κ |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Monoclonal;Recombinant |
Immunogen | Recombinant Human BMP-4 protein |
Abbre | BMP-4 |
Synonyms | OFC, DVR, MGC, ZGC, Bone morphogenetic protein, zbmp, MCOPS, BMP, BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, BMP 2B, BMP 4, BMP-2B, BMP-4, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, MGC100779, zbmp-4, zgc:100779, DVR4, BMP-4 |
Swissprot | |
Cellular Localization | Secreted, extracellular space, extracellular matrix. |
Concentration | 0.2 mg/mL |
Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
Purification Method | Protein A |
Research Areas | Cardiovascular, Signal Transduction, Stem Cells, Cancer, Developmental Biology |
Clone No. | 9B8 |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines. |
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Other Formats
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Unconjugated
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