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Recombinant BMP-4 Monoclonal Antibody - 1
  • Recombinant BMP-4 Monoclonal Antibody - 1
  • Recombinant BMP-4 Monoclonal Antibody - 2
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100μL $ 320.00
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50μL $ 211.00
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For research use only.

Verified Samples Verified Samples in IHC: Human appendix
Dilution IHC 1:200-1:1000
Isotype IgG,κ
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Monoclonal;Recombinant
Immunogen Recombinant Human BMP-4 protein
Abbre BMP-4
Synonyms OFC,  DVR,  MGC,  ZGC,  Bone morphogenetic protein,  zbmp,  MCOPS,  BMP,  BMP4,  BMP2B,  BMP2B1,  MCOPS6,  OFC11,  ZYME,  BMP 2B,  BMP 4,  BMP-2B,  BMP-4,  Bone morphogenetic protein 2B,  Bone morphogenetic protein 4,  MGC100779,  zbmp-4,  zgc:100779,  DVR4,  BMP-4
Swissprot
Cellular Localization Secreted, extracellular space, extracellular matrix.
Concentration 0.2 mg/mL
Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method Protein A
Research Areas Cardiovascular,  Signal Transduction,  Stem Cells,  Cancer,  Developmental Biology
Clone No. 9B8
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6) [MIM:607932]; also known as microphthalmia and pituitary anomalies or microphthalmia with brain and digit developmental anomalies. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. MCOPS6 is characterized by microphthalmia/anophthalmia associated with facial, genital, skeletal, neurologic and endocrine anomalies.,Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.,online information:Bone morphogenetic protein 4 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD.,tissue specificity:Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
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Unconjugated

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