Recombinant Bmi-1 Monoclonal Antibody (AN301273L)

For research use only.
Verified Samples | Verified Samples in IHC: Human tonsil |
Dilution | IHC 1:100-1:500 |
Isotype | IgG,κ |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Monoclonal;Recombinant |
Immunogen | Recombinant Human Bmi-1 protein |
Abbre | Bmi-1 |
Synonyms | RNF, BMI, PCGF, flvi-2/bmi, FLVI2/BMI, BMI1, FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1, Bmi-1 |
Swissprot | |
Cellular Localization | Nucleus, Cytoplasm. |
Concentration | 0.2 mg/mL |
Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
Purification Method | Protein A |
Research Areas | Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer |
Clone No. | 7B9 |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. |
Other Clones
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Other Formats
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Unconjugated
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