Recombinant Bile salt-activated lipase/CEL Monoclonal Antibody (AN300536P)

For research use only.
Verified Samples | Verified Samples in IHC: Mouse pancreas |
Dilution | IHC-P 1:100-1:500 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse |
Applications | IHC-P |
Clonality | Monoclonal |
Immunogen | Recombinant Mouse Bile salt-activated lipase/CEL Protein |
Abbre | CEL |
Synonyms | Lip, Lip1, Cel |
Swissprot | |
Tissue Specificity | EXpressed by eosinophils. |
Concentration | 1 mg/mL |
Buffer | 0.2 μm filtered solution in PBS |
Purification Method | Protein A |
Clone No. | 7A13 |
Conjugation | Unconjugated |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Shipping | Ice bag |
background | CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL cause maturity-onset diabetes of the young as well as pancreatic exocrine dysfunction. The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. |
Other Clones
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Other Formats
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Unconjugated
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