Recombinant beta-Catenin/CTNNB1 Monoclonal Antibody (AN300396P)

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For research use only.
Verified Samples |
Verified Samples in IHC: Human skin, Human colon Verified Samples in IF: A431 Verified Samples in FCM: Hela |
Dilution | IHC-P 1:100-1:500, ICC/IF :1:20-1:100, FCM 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC-P, IF, FCM |
Clonality | Monoclonal |
Immunogen | Recombinant Human beta-Catenin/CTNNB1 protein |
Abbre | CTNNB1 |
Synonyms | MRD, PRO, Catenin beta, SW-cl, OK/SW-cl, CTNNB, MRD19, armadillo, beta Catenin, CTNNB1, Beta-catenin, Catenin beta-1, OK, SW-cl.35, OK/SW-cl.35, PRO2286, 88kDa, beta 1, Cadherin associated protein, Catenin (cadherin associated protein), Catenin beta 1, CATNB, CHBCAT, CTNB1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289 |
Swissprot | |
Tissue Specificity | Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level). Expressed in breast cancer tissues (at protein level) |
Concentration | 1 mg/mL |
Buffer | 0.2 μm filtered solution in PBS |
Purification Method | Protein A |
Research Areas | Signal Transduction, Neuroscience, Stem Cells, Cancer, Cardiovascular |
Clone No. | 9D1 |
Conjugation | Unconjugated |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Shipping | Ice bag |
background | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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