RBM15 Polyclonal Antibody (E-AB-18870)

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All	Size	Price	Qty
	200μL	$ 399.00
	120μL	$ 240.00
	60μL	$ 143.00
	20μL	$ 73.00

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Verified Samples	Verified Samples in IHC: Human esophagus cancer
Dilution	IHC 1:50-1:300
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	IHC
Clonality	Polyclonal
Immunogen	Fusion protein of human RBM15
Abbre	RBM15
Synonyms	OTT, OTT1, One twenty two protein, One-twenty two protein 1, Putative RNA-binding protein 15, RBM15, RNA binding motif protein 15, RNA-binding motif protein 15
Swissprot	Q96T37
Cellular Localization	Nucleus.
Concentration	1.2 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Antigen affinity purification
Research Areas	Epigenetics and Nuclear Signaling, Stem Cells
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated