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For research use only.

Verified Samples Verified Samples in IHC: Human breast cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human RBFOX2
Abbre RBFOX2
Synonyms FOX2,  FXH,  Fox 1 homologue,  Fox-1 homolog B,  HNRBP2,  HRNBP2,  Hexaribonucleotide-binding protein 2,  RBFOX2,  RFOX2,  RNA binding motif protein 9,  RNA binding protein 9,  RNA binding protein fox-1 homolog 2,  RNA-binding moti,  Repressor of tamoxifen transcriptional activity
Swissprot
Cellular Localization Nucleus. Cytoplasm.
Concentration 1.44 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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