Rat REN Antibody Pair Set (E-KAB-0688)
For research use only.
| Background |
Renin is a secreted endopeptidase that plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen,which is the only known physiological substrate of Renin. The 406 aa precursor includes a signal peptide (aa 1 - 23),a propeptide (aa 24 - 66),and a mature chain (aa 67 - 406). It is an aspartyl protease that cleaves angiotensinogen to form angiotensin I. Renal Renin (Renin-1) is synthesized as a 381 aa proform (aa 22 - 402). In the kidney,prorenin is proteolytically cleaved after Thr71 to generate a mature enzyme.
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| Synonyms |
Angiotensinogenase, FLJ10761, HNFJ2, Prorenin, REN, renin precursor, renal, Renin
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| Swissprot | |
| Reactivity |
Rat
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| Specificity |
Detects Rat REN in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Rat REN concentrations in serum, plasma and other biological fluids.
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