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For research use only.
| Background | LPS-induced CXC chemokine (LIX) is a murine chemokine similar to two human chemokines, ENA-78 (CXCL5) and GCP-2 (CXCL6). Mouse LIX can be produced by many immune cells, such as macrophages, eosinophils , as well as non-immune cells including mesothelial cells, and fibroblasts. Increased serum LIX has been observed in obesity and insulin resistance in mice and humans and is associated with complications of diabetes including nephropathy and atherosclerosis. It is mainly produced when induced by LPS, IL-17 and/or TNF-α. According to the previous studies, cancer cell autonomous secretion of LIX as sufficient to drive infiltration of mature, protumorigenic neutrophils in a mouse model of non-small cell lung cancer (NSCLC). |
| Synonyms | LIX |
| Reactivity | Rat |
| Specificity | Detects Rat LIX in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
| Introduction | This Antibody Pair Kit applies to the sandwich ELISA assay. |
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Biotin
