RASA2 Polyclonal Antibody (E-AB-13557)

For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human ovarian cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human RASA2 |
Abbre | RASA2 |
Synonyms | GAP1m, GTPase activating protein of RAS, RAS p21 protein activator 2, RASA2, Ras GTPase activating protein 2, Ras GTPase-activating protein 2, Rasa2 |
Swissprot | |
Cellular Localization | Cytoplasm. Cytoplasm>perinuclear region. |
Concentration | 0.9 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein; a compound suggested to function as a second messenger. |
Other Clones
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Other Formats
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Unconjugated
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