RAPH1 Polyclonal Antibody (E-AB-65342)

For research use only.
Verified Samples |
Verified Samples in IF: C6, L929 |
Dilution | IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human RAPH1 (NP_998754.1). |
Abbre | RAPH1 |
Synonyms | ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RAPH1, RMO1, RalGDS/AF-6 |
Swissprot | |
Cellular Localization | Cell membrane, Cell projection, lamellipodium, Cell projection, filopodium, Cytoplasm, cytoskeleton, Recruited to the membrane, via the PH domain, by the phosphoinositide, PI(3, 4)P2, Colocalizes with ENAH/VASP at the tips of lamellipodia and filopodia, Also colocalizes with the pathogens, Vaccinia and Enteropathogenic E,coli (EPEC) at the interface between the pathogen and their actin. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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