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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil
Dilution IHC 1:40-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human RAPGEF1
Abbre RAPGEF1
Synonyms C3G,  C3G protein,  CRK SH3 binding GNRP,  CRK SH3-binding GNRP,  DKFZp781P1719,  GRF 2,  GRF2,  Guanine nucleotide releasing factor 2,  Guanine nucleotide releasing factor 2 (specific for crk proto oncogene),  Guanine nucleotide-releasing factor 2,  OTTHUMP00000064558,  Prote
Swissprot
Concentration 1.32 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a human guanine nucleotide exchange factor.It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases.This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Other Clones

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Unconjugated

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