RACGAP1 Polyclonal Antibody (E-AB-70169)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse testis, Mouse thymus |
| Dilution | IHC 1:200-1:800 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein corresponding to Mouse Racgap1 |
| Abbre | RACGAP1 |
| Synonyms | CYK4, GAP, GTPase activating protein, Gap1, HsCYK-4, ID GAP, KIAA1478, Male germ cell RacGap, MgcRacGAP, Protein CYK4 homolg, Protein CYK4 homolog, RACGAP 1, RGAP1, Rac GTPase activating protein 1, Rac GTPase-activating protein 1, Racgap1 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Cytoplasm>cytoskeleton>spindle. Cytoplasmic vesicle>secretory vesicle>acrosome. Cleavage furrow. Midbody. Colocalizes with RND2 in Golgi-derived proacrosomal vesicles and the acrosome (By similarity). During interphase, localized to the nucleus and cytoplasm along with microtubules, in anaphase, is redistributed to the central spindle and, in telophase and cytokinesis, to the midbody. Colocalizes with RHOA at the myosin contractile ring during cytokinesis. Colocalizes with ECT2 to the mitotic spindles during anaphase/metaphase, the cleavage furrow during telophase and at the midbody at the end of cytokinesis. Colocalizes with Cdc42 to spindle microtubules from prometaphase to telophase. |
| Concentration | 1.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Rac GTPase-activating protein 1 (RACGAP1),localized in the mitotic spindle,has guanosine triphosphatase-activating protein (GAP) activity for the Rho family GTPases. RACGAP1 has an important influence on the initiation of cytokinesis,control of cell growth and differentiation,regulation of spermatogenesis,and tumor metastasis. |
Other Clones
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Other Formats
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Unconjugated
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