RAB35 Polyclonal Antibody (E-AB-15468)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RAB35 |
| Abbre | RAB35 |
| Synonyms | GTP binding protein RAY, GTP-binding protein RAY, H ray, OTTHUMP00000240256, OTTHUMP00000240257, OTTHUMP00000240258, OTTHUMP00000240259, RAB1C, RAB35, RAB35 member RAS oncogene family, Rab35, Ras related protein rab 1c (GTP binding p, member RAS oncogene family |
| Swissprot | |
| Cellular Localization | Cell membrane. Membrane>clathrin-coated pit. Cytoplasmic vesicle>clathrin-coated vesicle. Endosome. Melanosome. Present on sorting endosomes and endosomal tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. Rab35 plays an important role in insulin-stimulated GLUT4 translocation in adipocytes.It is the target of TBC1D10A–C and that the intracellular accumulation of endosomal vesicles and impairs exosome secretion were occured when inhibition of Rab35 function.The surface of oligodendroglia in a GTP-dependent manner was localized Rab35, it increases the density of vesicles, and may have a function in docking or tethering. |
Other Clones
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Other Formats
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Unconjugated
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