RAB21 Polyclonal Antibody (E-AB-63624)
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For research use only.
| Verified Samples |
Verified Samples in IF: C6, NIH/3T3, U-2OS, U-2OS |
| Dilution | IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human RAB21 (NP_055814.1). |
| Abbre | RAB21 |
| Synonyms | RAB21 |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane, Golgi apparatus membrane, Early endosome membrane, Cytoplasmic vesicle membrane, Cleavage furrow, In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum, in polarized cells, observed in vesicles in the apical cytoplasm, During mitosis, in mid-telophase, localized in the ingressing cleavage furrow, In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. |
Other Clones
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Other Formats
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Unconjugated
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