Purified Anti-Mouse F4/80 Antibody[CI:A3-1] (E-AB-F0995A)

For research use only.
Alternate Names | Gpf480, Adgre1, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, Emr1 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Verified Samples | Verified Samples in FCM: Mouse peritoneal macrophages |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance. |
Immunogen | Recombinant Mouse F4/80 protein |
Abbre | F4/80 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Isotype | Rat IgG2b, κ |
Applications |
FCM
|
Research Areas | Cell Biology;Immunology;Innate Immunity;Neuroinflammation;Neuroscience |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 500
Elab Fluor®Violet 610
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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