Purified Anti-Mouse CD132 Antibody[3E12] (E-AB-F1015A)

For research use only.
Alternate Names | CD132, Cytokine receptor common subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, Il2rg, Interleukin-2 receptor subunit gamma, gammaC, p64 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID). |
Abbre | CD132 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype | Rat IgG2b, κ |
Applications |
FCM
|
Research Areas | Immunology |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
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Biotin
None (AF/LE)
Unconjugated
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