Purified Anti-Mouse CD105 Antibody[MJ7/18] (E-AB-F1233A)

For research use only.
Alternate Names | HHT, ORW1, AI528660, AI662476, CD105, END, Endo, Endoglin, HHT1, ORW, S-endoglin, Edg, Eng, END, HHT1, ORW, ORW1, CD 105, CD105 antigen, EGLN, FLJ41744, Osler Rendu Weber syndrome 1, RP11 228B15.2, SN6 |
Clone No | |
Leadtime | Inquire |
Verified Samples | Verified Samples in FCM: Bend.3 |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. |
Immunogen | Recombinant Human CD105 protein |
Abbre | CD105 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Isotype | Rat IgG2a, κ |
Applications |
FCM
|
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
FITC
None (AF/LE)
PE
Unconjugated
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