Purified Anti-Human CD62L Antibody[DREG56] (E-AB-F1051A)

For research use only.
Alternate Names | CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell |
Clone No | |
Leadtime | Order now, ship in 3 days |
Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
Abbre | CD62L |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1, κ |
Applications |
FCM
|
Research Areas | Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 540
Elab Fluor®Violet 610
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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