Purified Anti-Human CD58 Antibody[TS2/9.1] (E-AB-F1068A)

For research use only.
Alternate Names | Ag3, CD58, LFA3, Lymphocyte function-associated antigen 3, Surface glycoprotein LFA-3 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. |
Abbre | CD58 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1, κ |
Applications |
FCM
|
Research Areas | Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 7
PE/Elab Fluor®594
Unconjugated
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