Purified Anti-Human CD57 Antibody[HNK-1] (E-AB-F1067A)

For research use only.
Alternate Names | HNK-1, Leu-7, NK-1 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
Abbre | CD57 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgM, κ |
Applications |
FCM
|
Research Areas | Costimulatory Molecules;Immunology |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®700
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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