Purified Anti-Human CD52 Antibody[Campath-1G] (AN004360P)
For research use only.
| Alternate Names | CDW, Epididymal secretory protein E, Human epididymis-specific protein, CAMPATH, CAMPATH-1, CAMPATH-1 antigen, CD52 antigen, CD52 molecule, Epididymal secretory protein E5, HEL-S-171mP, Human epididymis-specific protein 5, CDW52, HE5, CD52, HE5 |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. |
| Immunogen | Recombinant Human CD52 protein |
| Abbre | CD52 |
| Swissprot | |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rabbit IgG, κ |
| Applications |
FCM
|
| Research Areas | Immunology |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Unconjugated
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