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For research use only.
| Alternate Names | IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocyte |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). |
| Immunogen | Recombinant Human CD32 protein |
| Abbre | CD32 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2b, κ |
| Applications | FCM;Block |
| Research Areas | Immunology;Innate Immunity |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Violet 450
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
Unconjugated
