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All Size Price Qty
100μg $ 154.00
25μg $ 63.00
100mg $ 18800.00
50mg $ 13150.00
25mg $ 7500.00
5mg $ 1900.00
1mg $ 460.00
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For research use only.

Alternate Names IDDM,  CCCKR,  CMKBR,  CC-CKR,  CKR,  CCR,  CKR5,  CCR-5,  CD195,  CKR-5,  CCCKR5,  CMKBR5,  IDDM22,  CC-CKR-5,  CCR5,  CCCKR5,  CC-CKR-5,  CCR-5,  CD195,  CKR-5,  CMKBR5,  IDDM22
Clone No
Leadtime Inquire
Verified Samples Verified Samples in FCM: Human peripheral blood lymphocytes
Dilution FCM 2 μg/mL(1×105-5×105 cells)
Background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
Immunogen Recombinant Human CD195 protein
Abbre CD195
Swissprot
Host Mouse
Reactivity Human
Clonality Monoclonal
Purification Method >98%, Protein A/G purified
Isotype Mouse IgG2a, κ
Applications
FCM
Research Areas Neuroscience;Immunology;Microbiology;Signal Transduction;Cancer;Cardiovascular
Concentration
≥ 1 mg/mL
Conjugation Unconjugated
Storage Buffer Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date 12 months
Shipping Ice bag
Other Clones

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Other Formats

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APC

Elab Fluor®488

Elab Fluor®647

Elab Fluor®700

FITC

PE

PE/Cyanine 7

PE/Elab Fluor®594

PerCP/Cyanine 5.5

Unconjugated

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