Purified Anti-Human CD193 Antibody[5E8] (E-AB-F1303A)
For research use only.
| Alternate Names | CKR, B-lymphocyte antigen CD, MIP1-alpha receptor like, Differentiation antigen CD, C-C chemokine receptor type, Neural cell adhesion molecule, CMKBR, N-CAM, CC-CKR, CC CKR, CCR3, CC-CKR-3, CD193, CKR3, CMKBR3, B-lymphocyte antigen CD19, C-C chemokine receptor type 3, CC CKR3, CCR, Cd19, Differentiation antigen CD19, eotaxin receptor, MIP1-alpha receptor like-2, NCAM, NCAM1, NCAM-1, N-CAM-1, Neural cell adhesion molecule 1, C-C CKR-3, C-C motif chemokine receptor 3, CD_antigen: CD193, cluster of differentiation 193, Eosinophil eotaxin receptor |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocytes |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. |
| Immunogen | Recombinant Human CD193 protein |
| Abbre | CD193 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse C57BL/6 IgG2b, κ |
| Applications |
FCM
|
| Research Areas | Immunology;Signal Transduction |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
Unconjugated
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