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For research use only.
| Alternate Names | Fc gamma receptor, Fc gamma receptor 3, FcγRIII |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Immunogen | Recombinant Human CD16 protein |
| Abbre | CD16 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Applications | FCM;Block |
| Research Areas | Immunology;Innate Immunity |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 540
Elab Fluor®Violet 610
FITC
None (AF/LE)
PE
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP
PerCP/Cyanine 5.5
Unconjugated
