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For research use only.
Verified Samples | Verified Samples in IHC: Human ovarian cancer, Human thyroid cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human PTPA |
Abbre | PTPA |
Synonyms | regulatory subunit B-prime, KIAA0044 , MGC2184 , PP2A, PP2A phosphatase activator , PP2A subunit B', PP2A subunit B' PR53 isoform , PP2A subunit B' isoform PR53, PPP2R4, PR53 , PR53 isoform, Phosphotyrosyl phosphatase activator, Pro, Protein phosphatase 2, subunit B'' |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. |
Concentration | 1.08 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Other Clones
1 Results
Other Formats
1 Results
Unconjugated