PTP4A2 Polyclonal Antibody (E-AB-65270)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat kidney, Human colon, Mouse lung Verified Samples in IF: C6 |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human PTP4A2 (NP_536316.1). |
| Abbre | PTP4A2 |
| Synonyms | HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, PTP4A, PTP4A2, PTPCAAX2, ptp-IV1a, ptp-IV1b |
| Swissprot | |
| Cellular Localization | Cell Membrane, Early Endosome and Cytoplasm. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
Other Clones
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Other Formats
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Unconjugated
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