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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human ovarian cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PTGDR2
Abbre PTGDR2
Synonyms CD294,  CD294 antigen,  CRTH 2,  CRTH2,  Chemoattractant receptor homologous molecule expressed on Th2 cells,  Chemoattractant receptor-homologous molecule expressed on Th2 cells,  DL1R,  DP2 prostaglandin receptor,  G Protein Coupled ,  chemoattractant receptor-homologous
Swissprot
Cellular Localization Cell membrane.
Concentration 0.78 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.PTGDR2 (Prostaglandin D2 Receptor 2) is a Protein Coding gene. Diseases associated with PTGDR2 include Folliculitis and Eosinophilic Pustular Folliculitis. Among its related pathways are Peptide ligand-binding receptors and Ibuprofen Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity and prostaglandin F receptor activity. An important paralog of this gene is FPR3.
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Unconjugated

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