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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human esophagus cancer
Dilution IHC 1:40-1:250
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human PRAME
Abbre PRAME
Synonyms 4930534P07Rik,  CT130,  Cancer/testis antigen 130,  MAPE,  Melanoma antigen preferentially expressed in tumors,  OIP 4,  OIP-4,  OIP4 ,  OPA interacting protein 4,  OPA-interacting protein 4,  Opa interacting protein OIP4,  PRAME,  Preferentially expressed antigen in melan
Swissprot
Cellular Localization Nucleus. Cell membrane.
Concentration 1.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Tags and Cell markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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