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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human PPM1B
Abbre PPM1B
Synonyms MGC21657,  OTTHUMP00000158953,  OTTHUMP00000158954,  OTTHUMP00000158955,  OTTHUMP00000202394,  OTTHUMP00000202395,  OTTHUMP00000202399,  PP2C beta,  PP2C beta X,  PP2C-beta,  PP2CB,  PP2Cbeta,  PPC2BETAX,  PPM 1B,  PPM1B,  Ppm1b,  Protein phosphatase 1B (formerly 2C) magnesium dependent
Swissprot
Concentration 1.44 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Cell Biology,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Other Clones

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Unconjugated

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