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For research use only.
| Background | EGFR;also named as ERBB1;is a cell-surface receptor for members of the epidermal growth factor family ( EGF-family ) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12;encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression;including cell proliferation;apoptosis;angiogenesis;and metastatic spread. Mutations in this gene are associated with lung cancer. |
| Synonyms | ErbB-1, ErbB1, ERBB, HER1, mENA |
| Swissprot | |
| Reactivity | Porcine |
| Specificity | Detects Porcine EGFR in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
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Biotin
