PERK Polyclonal Antibody (E-AB-70363)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human lung cancer, Human liver cancer, Human colon |
| Dilution | IHC 1:400-1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Human PERK |
| Abbre | PERK |
| Synonyms | DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, HRI, Heme regulated EIF2 alpha kinase, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinas |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane. |
| Concentration | 1.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis.It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins.Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Other Clones
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Other Formats
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Unconjugated
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