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For research use only.
Alternate Names | MIP1-alpha receptor like-2eotaxin receptor, C-C chemokine receptor type 3, CC CKR3, CCR, CCR3 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. |
Abbre | CD193 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2b, κ |
Isotype Control | E-AB-F09812G |
Applications | FCM |
Research Areas | Immunology |
Cellular Localization | Membrane |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PE/Cyanine 5 |
Conjugation Information | PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
Unconjugated
