PE Anti-Mouse FcεRIα Antibody[MAR-1] (E-AB-F1188UD)
For research use only.
| Alternate Names | Fc-epsilon RI-alpha, FcERI, Fcer1a, High affinity immunoglobulin epsilon receptor subunit alpha |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
| Abbre | FcεRIα |
| Swissprot | |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Armenian Hamster IgG |
| Isotype Control | E-AB-F09853D |
| Applications |
FCM
|
| Research Areas | Immunology;Innate Immunity |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
0.2 mg/mL
|
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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