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For research use only.
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer. |
Abbre | CD195 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2a, κ |
Isotype Control | E-AB-F09802D |
Applications | FCM |
Cellular Localization | Membrane |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PE |
Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
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