PE Anti-Human CD193/CCR3 Antibody[5E8] (E-AB-F1303D)
For research use only.
| Alternate Names | MIP1-alpha receptor like-2eotaxin receptor, C-C chemokine receptor type 3, CC CKR3, CCR, CCR3 |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. |
| Abbre | CD193 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | E-AB-F09812D |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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APC
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Violet 450
FITC
PE
PE/Cyanine 5
Unconjugated
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