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For research use only.

Verified Samples Verified Samples in IHC: Human cervical cancer, Human tonsil
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human PDHA1
Abbre PDHA1
Synonyms E1 alpha polypeptide 1,  ODPA,  PDH,  PDHA,  PDHA1,  PDHCE1A,  PDHE1 A type I,  PDHE1-A type I,  PHE1A,  Pyruvate Dehydrogenase (lipoamide) alpha 1,  Pyruvate Dehydrogenase E1 alpha,  Pyruvate dehydrogenase E1 component subunit alpha,  Pyruvate dehydrogenase complex,  somatic form
Swissprot
Cellular Localization Mitochondrion matrix.
Concentration 0.84 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background PDHA1(Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial) is also named as PHE1A.It is one of the 3 enzymes of the pyruvate dehydrogenase complex which is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA.It has 4 isoforms produced by alternative splicing.Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS).
Other Clones

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Unconjugated

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