PDGFR beta Polyclonal Antibody (E-AB-67422)

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For research use only.
Verified Samples |
Verified Samples in IHC: Rat lung, Rat spleen, Rat kidney, Human placenta Verified Samples in IF: C6, NIH/3T3 |
Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC, IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human PDGFR beta (NP_002600.1). |
Abbre | PDGFR beta |
Synonyms | CD140B, IBGC4, IMF1, JTK12, KOGS, PDGF Receptor beta, PDGFR, PDGFR beta, PDGFR-1, PDGFR1, PDGFRB, PENTT |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
Other Clones
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Other Formats
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Unconjugated
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