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For research use only.

Verified Samples Verified Samples in IHC: Rat lung, Rat spleen, Rat kidney, Human placenta
Verified Samples in IF: C6, NIH/3T3
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human PDGFR beta (NP_002600.1).
Abbre PDGFR beta
Synonyms CD140B,  IBGC4,  IMF1,  JTK12,  KOGS,  PDGF Receptor beta,  PDGFR,  PDGFR beta,  PDGFR-1,  PDGFR1,  PDGFRB,  PENTT
Swissprot
Cellular Localization Membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Other Clones

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Unconjugated

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