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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human thyroid cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human NTAN1
Abbre NTAN1
Synonyms N terminal Asn amidase,  N terminal asparagine amidase ,  N terminal asparagine amidohydrolase,  NTN-amidase,  PNAA ,  PNAD ,  Protein N-terminal Asn amidase,  Protein N-terminal asparagine amidase,  Protein N-terminal asparagine amidohydrolase,  Protein NH2-terminal aspar
Swissprot
Cellular Localization Cytoplasmic
Concentration 1.32 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Other Clones

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Unconjugated

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