NRG1-beta 1 Monoclonal Antibody (AN200087P)
For research use only.
| Verified Samples | Verified Samples in WB: Human NRG1-beta1, Human NRG1-alpha |
| Dilution | WB 1:500-1:2000, |
| Isotype | IgG2b |
| Host | Mouse |
| Reactivity | Human |
| Applications | WB |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1. |
| Abbre | NRG1 |
| Synonyms | NRG, MST, HRG1-beta, NRG1-beta, Pro-neuregulin, Neuregulin-1 beta, ARIA, EGF, GGF2, HRG, HRG1, HRG1-beta 1, MST131, Neuregulin-1 beta 1, NRG1-beta 1, Pro-neuregulin-1, GGF, HGL, HRGA, NDF, SMDF, NRG1, Acetylcholine receptor-inducing activity, alpha (45kD, Breast cancer cell differentiation factor p45, CHICK, ERBB2 p185-activator), Glial growth factor, Heregulin, homolog of, membrane-bound isoform, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, NRG 1, NRG1-IT2, OTTHUMP00000225398, OTTHUMP00000225419, OTTHUMP00000225420, OTTHUMP00000225421, OTTHUMP00000225422, OTTHUMP00000225477, OTTHUMP00000225545, OTTHUMP00000230603, OTTHUMP00000230605, ProNRG1, Pro-NRG1, Sensory and motor neuron-derived factor |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Neuroscience |
| Clone No. | 5H10 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis. |
Other Clones
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Unconjugated
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