NGEF Polyclonal Antibody (E-AB-18859)

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All	Size	Price	Qty
	200μL	$ 399.00
	120μL	$ 240.00
	60μL	$ 143.00
	20μL	$ 73.00

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For research use only. Order now, ship in 3 days

Verified Samples	Verified Samples in IHC: Human tonsil, Human liver cancer
Dilution	IHC 1:40-1:200
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Polyclonal
Immunogen	Fusion protein of human NGEF
Abbre	NGEF
Synonyms	neuronal, ARHGEF27, EPHEXIN, Eph receptor-interacting exchange protein, Eph-interacting exchange protein, Ephexin-1, Guanine nucleotide exchange factor, NGEF, Neuronal guanine nucleotide exchange factor, Ngef
Swissprot	Q8N5V2
Cellular Localization	Cytoplasm. Membrane. Cell projection>growth cone. Associated with membranes. Localizes to axonal growth cones.
Concentration	0.6 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Antigen affinity purification
Research Areas	Neuroscience, Signal transduction
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated