NEK2 Polyclonal Antibody (E-AB-10922)

For research use only.
Verified Samples |
Verified Samples in WB: LoVo |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human NEK2 |
Abbre | NEK2 |
Synonyms | HSPK 21, HsPK21, NEK 2, NEK2, NEK2A, NIMA (never in mitosis gene a) related kinase 2, NIMA related kinase 2, Never in mitosis A-related kinase 2, NimA like protein kinase 1, NimA related protein kinase 2, NimA-like protein kinase 1, NimA-related protein kinase |
Swissprot | |
Calculated MW | 52 kDa |
Cellular Localization | Cytoplasm, Predominantly cytoplasmic, Nucleus>nucleolus, Has a nucleolar targeting/ retention activity via a coiled-coil domain at the C-terminal end and Nucleus, Chromosome>centromere, Chromosome>centromere>kinetochore, Co-localizes with SGOL1 and MAD1L1 at the kinetochore, Not associated with kinetochore in the interphase but becomes associated with it upon the breakdown of the nuclear envelope. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. |
Other Clones
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Other Formats
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Unconjugated
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