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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human liver cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human PVRL4
Abbre NECTIN4
Synonyms DKFZp686K05193,  EDSS1,  Ig superfamily receptor LNIR,  Nectin 4,  Nectin-4,  PRR4,  PVRL4,  Processed poliovirus receptor-related protein 4,  poliovirus receptor-related 4,  pvrl4
Swissprot
Cellular Localization Cell membrane. Cell junction>adherens junction. Colocalizes with MLLT4 at cadherin-based adherens junctions and Secreted. The secreted form is found in breast tumor patients.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the nectin family.The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain.It is involved in cell adhesion through trans-homophilic and -heterophilic interactions.It is a single-pass type I membrane protein.The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE.The secreted form is found in both breast tumor cell lines and breast tumor patients.
Other Clones

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Unconjugated

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