Mouse OPG Antibody Pair Set (E-KAB-0091)
For research use only.
| Background |
Osteoprotegerin (OPG), also known as TNFRSF11B or OCIF, is a member of the tumor necrosis factor receptor super family (TNFRSF). It is a secreted glycoprotein that inhibits osteoclastogenesis and is involved in the regulation of bone density. Osteoprotegerin acts as decoy receptor for receptor activator of nuclear factor-kappa B ligand (RANKL) and neutralizes its function in osteoclastogenesis. Osteoprotegerin may function as a soluble decoy receptor for tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) and inhibits TRAIL-induced apoptosis. TRAIL blocks osteoprotegerin mediated inhibition of osteoclastogenesis.
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| Synonyms |
Tnfrsf11b, Ocif, Opg, Osteoprotegerin, Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse OPG in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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