Mouse LAB7-1 Antibody Pair Set (E-KAB-0722)
For research use only.
| Background |
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1,B7,and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages,and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells,macrophages,and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation,proliferation,and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152,also known as CTLA-4,to deliver an inhibitory signal to T cells.
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| Synonyms |
CD80, CD28LG, CD28LG1, BB1, B7-1 Antigen, T-lymphocyte activation antigen CD80, CTLA-4 counter-receptor B7.1
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse LAB7-1 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Mouse LAB7-1 concentrations in serum, plasma and other biological fluids.
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